Serveur d'exploration Chloroquine

Attention, ce site est en cours de développement !
Attention, site généré par des moyens informatiques à partir de corpus bruts.
Les informations ne sont donc pas validées.

Phenolic aporphine-benzylisoquinoline alkaloids from Thalictrum faberi

Identifieur interne : 002604 ( Main/Exploration ); précédent : 002603; suivant : 002605

Phenolic aporphine-benzylisoquinoline alkaloids from Thalictrum faberi

Auteurs : Long-Ze Lin [États-Unis] ; Shu-Fang Hu [États-Unis] ; Min Chu [États-Unis] ; Tze-Ming Chan [États-Unis] ; Heebyung Chai [États-Unis] ; Cindy K. Angerhofer [États-Unis] ; John M. Pezzuto [États-Unis] ; Geoffrey A. Cordell [États-Unis]

Source :

RBID : ISTEX:15EA78775D12E69621B976C706CB4FDAFDF737AB

English descriptors

Abstract

Abstract: From the roots of Thalictrum faberi, six new phenolic aporphine-benzylisoquinoline alkaloids, 3-hydroxy-6′-desmethyl-9-O-methylthalifaboramine (1), 3-hydroxythalifaboramine (2), 6′-desmethylthalifaboramine (3); 3,5′-dihydroxythalifaboramine (4), 5′-hydroxythalifaboramine (5) and 3-hydroxy-6′-desmethylthalifaboramine (6) were isolated. Their structures were established through the use of one- and two-dimensional NMR techniques. All of the tested alkaloids showed potent cytotoxic and antimalarial activities.

Url:
DOI: 10.1016/S0031-9422(98)00580-9


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

<record>
<TEI wicri:istexFullTextTei="biblStruct">
<teiHeader>
<fileDesc>
<titleStmt>
<title>Phenolic aporphine-benzylisoquinoline alkaloids from Thalictrum faberi</title>
<author>
<name sortKey="Lin, Long Ze" sort="Lin, Long Ze" uniqKey="Lin L" first="Long-Ze" last="Lin">Long-Ze Lin</name>
</author>
<author>
<name sortKey="Hu, Shu Fang" sort="Hu, Shu Fang" uniqKey="Hu S" first="Shu-Fang" last="Hu">Shu-Fang Hu</name>
</author>
<author>
<name sortKey="Chu, Min" sort="Chu, Min" uniqKey="Chu M" first="Min" last="Chu">Min Chu</name>
</author>
<author>
<name sortKey="Chan, Tze Ming" sort="Chan, Tze Ming" uniqKey="Chan T" first="Tze-Ming" last="Chan">Tze-Ming Chan</name>
</author>
<author>
<name sortKey="Chai, Heebyung" sort="Chai, Heebyung" uniqKey="Chai H" first="Heebyung" last="Chai">Heebyung Chai</name>
</author>
<author>
<name sortKey="Angerhofer, Cindy K" sort="Angerhofer, Cindy K" uniqKey="Angerhofer C" first="Cindy K" last="Angerhofer">Cindy K. Angerhofer</name>
</author>
<author>
<name sortKey="Pezzuto, John M" sort="Pezzuto, John M" uniqKey="Pezzuto J" first="John M" last="Pezzuto">John M. Pezzuto</name>
</author>
<author>
<name sortKey="Cordell, Geoffrey A" sort="Cordell, Geoffrey A" uniqKey="Cordell G" first="Geoffrey A" last="Cordell">Geoffrey A. Cordell</name>
</author>
</titleStmt>
<publicationStmt>
<idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:15EA78775D12E69621B976C706CB4FDAFDF737AB</idno>
<date when="1999" year="1999">1999</date>
<idno type="doi">10.1016/S0031-9422(98)00580-9</idno>
<idno type="url">https://api.istex.fr/ark:/67375/6H6-4516MDB9-9/fulltext.pdf</idno>
<idno type="wicri:Area/Istex/Corpus">002228</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">002228</idno>
<idno type="wicri:Area/Istex/Curation">002228</idno>
<idno type="wicri:Area/Istex/Checkpoint">001419</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">001419</idno>
<idno type="wicri:doubleKey">0031-9422:1999:Lin L:phenolic:aporphine:benzylisoquinoline</idno>
<idno type="wicri:Area/Main/Merge">002640</idno>
<idno type="wicri:Area/Main/Curation">002604</idno>
<idno type="wicri:Area/Main/Exploration">002604</idno>
</publicationStmt>
<sourceDesc>
<biblStruct>
<analytic>
<title level="a">Phenolic aporphine-benzylisoquinoline alkaloids from Thalictrum faberi</title>
<author>
<name sortKey="Lin, Long Ze" sort="Lin, Long Ze" uniqKey="Lin L" first="Long-Ze" last="Lin">Long-Ze Lin</name>
<affiliation wicri:level="4">
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Program for Collaborative Research in the Pharmaceutical Sciences, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago IL, 60612-7231</wicri:regionArea>
<orgName type="university">Université de l'Illinois à Chicago</orgName>
<placeName>
<settlement type="city">Chicago</settlement>
<region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Hu, Shu Fang" sort="Hu, Shu Fang" uniqKey="Hu S" first="Shu-Fang" last="Hu">Shu-Fang Hu</name>
<affiliation wicri:level="4">
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Program for Collaborative Research in the Pharmaceutical Sciences, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago IL, 60612-7231</wicri:regionArea>
<orgName type="university">Université de l'Illinois à Chicago</orgName>
<placeName>
<settlement type="city">Chicago</settlement>
<region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Chu, Min" sort="Chu, Min" uniqKey="Chu M" first="Min" last="Chu">Min Chu</name>
<affiliation wicri:level="2">
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Schering–Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, NJ 07033</wicri:regionArea>
<placeName>
<region type="state">New Jersey</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Chan, Tze Ming" sort="Chan, Tze Ming" uniqKey="Chan T" first="Tze-Ming" last="Chan">Tze-Ming Chan</name>
<affiliation wicri:level="2">
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Schering–Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, NJ 07033</wicri:regionArea>
<placeName>
<region type="state">New Jersey</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Chai, Heebyung" sort="Chai, Heebyung" uniqKey="Chai H" first="Heebyung" last="Chai">Heebyung Chai</name>
<affiliation wicri:level="4">
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Program for Collaborative Research in the Pharmaceutical Sciences, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago IL, 60612-7231</wicri:regionArea>
<orgName type="university">Université de l'Illinois à Chicago</orgName>
<placeName>
<settlement type="city">Chicago</settlement>
<region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Angerhofer, Cindy K" sort="Angerhofer, Cindy K" uniqKey="Angerhofer C" first="Cindy K" last="Angerhofer">Cindy K. Angerhofer</name>
<affiliation wicri:level="4">
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Program for Collaborative Research in the Pharmaceutical Sciences, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago IL, 60612-7231</wicri:regionArea>
<orgName type="university">Université de l'Illinois à Chicago</orgName>
<placeName>
<settlement type="city">Chicago</settlement>
<region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Pezzuto, John M" sort="Pezzuto, John M" uniqKey="Pezzuto J" first="John M" last="Pezzuto">John M. Pezzuto</name>
<affiliation wicri:level="4">
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Program for Collaborative Research in the Pharmaceutical Sciences, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago IL, 60612-7231</wicri:regionArea>
<orgName type="university">Université de l'Illinois à Chicago</orgName>
<placeName>
<settlement type="city">Chicago</settlement>
<region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Cordell, Geoffrey A" sort="Cordell, Geoffrey A" uniqKey="Cordell G" first="Geoffrey A" last="Cordell">Geoffrey A. Cordell</name>
<affiliation wicri:level="4">
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Program for Collaborative Research in the Pharmaceutical Sciences, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago IL, 60612-7231</wicri:regionArea>
<orgName type="university">Université de l'Illinois à Chicago</orgName>
<placeName>
<settlement type="city">Chicago</settlement>
<region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series>
<title level="j">Phytochemistry</title>
<title level="j" type="abbrev">PHYTO</title>
<idno type="ISSN">0031-9422</idno>
<imprint>
<publisher>ELSEVIER</publisher>
<date type="published" when="1999">1999</date>
<biblScope unit="volume">50</biblScope>
<biblScope unit="issue">5</biblScope>
<biblScope unit="page" from="829">829</biblScope>
<biblScope unit="page" to="834">834</biblScope>
</imprint>
<idno type="ISSN">0031-9422</idno>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt>
<idno type="ISSN">0031-9422</idno>
</seriesStmt>
</fileDesc>
<profileDesc>
<textClass>
<keywords scheme="Teeft" xml:lang="en">
<term>Alkaloid</term>
<term>American chemical society</term>
<term>Antimalarial</term>
<term>Base peak</term>
<term>Chemical shift values</term>
<term>Cosy</term>
<term>Desmethylthalifaboramine</term>
<term>Faberi</term>
<term>Guinaudeau</term>
<term>Hmbc</term>
<term>Hmbc correlations</term>
<term>Hmbc spectrum</term>
<term>Hrms</term>
<term>Hussain</term>
<term>Leboeuf</term>
<term>Major results</term>
<term>Mass spectra</term>
<term>Meoh</term>
<term>Methoxy</term>
<term>Methoxy function</term>
<term>Methoxy functions</term>
<term>Methoxy groups</term>
<term>Methoxy signal</term>
<term>Natural products</term>
<term>Phenolic</term>
<term>Phenolic alkaloid</term>
<term>Phenolic alkaloids</term>
<term>Phenolic function</term>
<term>Phenolic functions</term>
<term>Phytochemistry</term>
<term>Roesy</term>
<term>Roesy spectrum</term>
<term>Seligman</term>
<term>Signal multiplicity</term>
<term>Thalictrum</term>
<term>Thalictrum faberi</term>
<term>Yellow powder</term>
</keywords>
</textClass>
<langUsage>
<language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">Abstract: From the roots of Thalictrum faberi, six new phenolic aporphine-benzylisoquinoline alkaloids, 3-hydroxy-6′-desmethyl-9-O-methylthalifaboramine (1), 3-hydroxythalifaboramine (2), 6′-desmethylthalifaboramine (3); 3,5′-dihydroxythalifaboramine (4), 5′-hydroxythalifaboramine (5) and 3-hydroxy-6′-desmethylthalifaboramine (6) were isolated. Their structures were established through the use of one- and two-dimensional NMR techniques. All of the tested alkaloids showed potent cytotoxic and antimalarial activities.</div>
</front>
</TEI>
<affiliations>
<list>
<country>
<li>États-Unis</li>
</country>
<region>
<li>Illinois</li>
<li>New Jersey</li>
</region>
<settlement>
<li>Chicago</li>
</settlement>
<orgName>
<li>Université de l'Illinois à Chicago</li>
</orgName>
</list>
<tree>
<country name="États-Unis">
<region name="Illinois">
<name sortKey="Lin, Long Ze" sort="Lin, Long Ze" uniqKey="Lin L" first="Long-Ze" last="Lin">Long-Ze Lin</name>
</region>
<name sortKey="Angerhofer, Cindy K" sort="Angerhofer, Cindy K" uniqKey="Angerhofer C" first="Cindy K" last="Angerhofer">Cindy K. Angerhofer</name>
<name sortKey="Chai, Heebyung" sort="Chai, Heebyung" uniqKey="Chai H" first="Heebyung" last="Chai">Heebyung Chai</name>
<name sortKey="Chan, Tze Ming" sort="Chan, Tze Ming" uniqKey="Chan T" first="Tze-Ming" last="Chan">Tze-Ming Chan</name>
<name sortKey="Chu, Min" sort="Chu, Min" uniqKey="Chu M" first="Min" last="Chu">Min Chu</name>
<name sortKey="Cordell, Geoffrey A" sort="Cordell, Geoffrey A" uniqKey="Cordell G" first="Geoffrey A" last="Cordell">Geoffrey A. Cordell</name>
<name sortKey="Hu, Shu Fang" sort="Hu, Shu Fang" uniqKey="Hu S" first="Shu-Fang" last="Hu">Shu-Fang Hu</name>
<name sortKey="Pezzuto, John M" sort="Pezzuto, John M" uniqKey="Pezzuto J" first="John M" last="Pezzuto">John M. Pezzuto</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002604 | SxmlIndent | more

Ou

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002604 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    ChloroquineV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     ISTEX:15EA78775D12E69621B976C706CB4FDAFDF737AB
   |texte=   Phenolic aporphine-benzylisoquinoline alkaloids from Thalictrum faberi
}}

Wicri

This area was generated with Dilib version V0.6.33.
Data generation: Wed Mar 25 22:43:59 2020. Site generation: Sun Jan 31 12:44:45 2021